Diabetes with Turner Syndrome | Turner Syndrome Foundation

Diabetes

Glucose Intolerance
Glucose intolerance occurs more frequently in persons with Turner Syndrome than in the general population; however, diabetes mellitus seems to be rare. Monitoring of fasting blood glucose concentrations should be considered in girls who are significantly overweight, have a strong family history of type 2 diabetes mellitus, are Hispanic or African American, or have signs of insulin resistance, such as acanthosis nigricans.

 

Diabetes with Turner Syndrome

Healthy women with Turner Syndrome are characterized by:

  • Impaired glucose tolerance
  • Insulin resistance
  • Low physical capacity
  • Enlarged type IIa muscle fibers, indicating diminished oxygen and substrate supply for metabolic processes
  • These findings could be indicative of a pre-diabetes state

Weight Management

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