FAQ – test

1. Worldwide estimates of vitamin D deficiency:
This estimate was based on each counties and/or regions that reported the incidence of vitamin D insufficiency (<30ng/mL) and deficiency (<20 ng/mL), multiplied by the given number of population in the country or the region. My estimates for vitamin D deficiency is approximately 2.3 billion and deficiency + insufficiency (the total) estimated is about 3.5 billion in the world. This comes to about 50% of the world’s population.
2. “What is all the hype about vitamin D deficiency these days?”
The prevalence of vitamin D deficiency is rising worldwide and approaching epidemic proportions, and most common among the vulnerable groups and elderly. Yet vast majorities of individuals have an undiagnosed and untreated vitamin D deficiency.
This is a real issues, which is getting worse; it has n been neglected for a while. This is consequently to a combination of several factors, but predominantly due to inadequate sun-exposure. Most patients who need vitamin D supplements are either not given or provide inadequate doses. Moreover, long-term adherence to oral supplementation is poor. Measurement of serum 25(OH)D is the most reliable way to evaluate vitamin D status.
Vitamin D deficiency is the most under-diagnosed and perhaps the most common medical condition in the world. Many estimate that more than 2 billion people worldwide across all ethnic and age groups have vitamin D deficiency. Many individuals in industrialized countries, especially in the northern hemisphere, have low serum vitamin D levels. Recent literature on vitamin D is full of controversies on its measurements, diagnosis, benefits, and the management of deficiency.
3. What are the reasons that we need adequate amounts of vitamin D?
Severe vitamin D deficiency leads to rickets in childhood and osteomalacia in adults. Low vitamin D levels may aggravate a variety of non-skeletal disorders including cancer, diabetes, metabolic syndrome, infectious diseases, and autoimmune disorders. In addition to enhancing calcium absorption from the intestine and mineralization of the osteoid tissue, vitamin D is important in many other physiological effects, including neuro-modulation, muscle strength and coordination, release of insulin, immune health. For example, cardiovascular morbidity and mortality are increased in patients with all levels of renal dysfunction, especially in those with low serum vitamin D levels.
4. Why vitamin D deficiency is common around the world including US?
Ultraviolet rays provide more than 80% of our vitamin D requirement; diet and supplements can augment it. The two major causes of vitamin D deficiency are the lack of exposure to sunlight and less than adequate dietary intakes.
5. What are the main health issues associated with vitamin D deficiency?
Widespread vitamin D deficiency may be related to the increasing incidences of cancer, type 2 diabetes, obesity, and heart disease remains to be determined. However, the relationship of vitamin D to the skeletal and non-skeletal systems and the significance of non-classic functions and targets of vitamin D need further studies.

©2017 Turner Syndrome Foundation

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